CD95 Antibody / FAS Immune Apoptosis Marker Antibody [clone FAS/3588] (V7883)

CD95 Antibody Human Tonsil Tissue IHC. Immunohistochemistry analysis of FFPE human tonsil tissue using CD95 Antibody (clone FAS/3588) demonstrates HRP-DAB brown membranous and cytoplasmic staining in lymphoid cells within germinal center and interfollicular regions, consistent with CD95 / FAS as an immune apoptosis marker regulating lymphocyte activation and programmed cell death, while surrounding stromal elements show minimal background; nuclei are counterstained blue. HIER: boil tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.

CD95 Antibody Microarray Specificity Validation. Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using CD95 Antibody (clone FAS/3588) demonstrates specific detection of FAS / CD95, an immune apoptosis marker involved in regulating lymphocyte survival and programmed cell death. These results confirm strong target specificity of the FAS/3588 mAb, with a dominant signal for FAS and limited off-target binding. Z- and S-score: The Z-score reflects the strength of signal generated when the antibody binds a protein on the array, expressed as standard deviations above the mean, while the S-score represents the difference between sequential Z-scores and indicates relative target specificity.