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- Email: info@nsjbio.com
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It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa (Workshop IV). This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
Optimal dilution of the CD71 antibody should be determined by the researcher.
The acute myeloid leukemia cell line KG1 was used as the immunogen for the CD71 antibody.
Store the CD71 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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