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Home >> Antibodies >> CD71 Antibody / Transferrin Receptor

CD71 Antibody / Transferrin Receptor [clone 66IG10] (V2261CF488)

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  Catalog No Formulation Size Price (USD)  
Image V2261CF488-100T 500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 Tests 519
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Flow cytometry testing of K562 cells with CF488 conjugated CD71 antibody (green, clone 66IG10), cells alone (black) and isotype control (gray).
Flow cytometry testing of K562 cells with CF488 conjugated CD71 antibody (green, clone 66IG10), cells alone (black) and isotype control (gray).
Availability 1-3 business days
Species Reactivity Human
Format CF488 Conjugate
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name 66IG10
Purity Protein G affinity chromatography
UniProt P02786
Localization Cell surface
Applications Flow cytometry : 5ul per test per one 10^6 cells in 0.1ml or 5ul per 100ul of whole blood
Immunofluorescence : 1-2ug/ml
Limitations This CD71 antibody is available for research use only.
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Description

It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Application Notes

Optimal dilution of the CD71 antibody should be determined by the researcher.

Immunogen

Recombinant human protein was used as the immunogen for this Transferrin receptor / CD71 antibody.

Storage

Store the CD71 antibody at 2-8oC, protected from light.

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