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Home >> Antibodies >> CD70 Antibody

CD70 Antibody [clone TNFS7/1026] (V3034)

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  Catalog No Formulation Size Price (USD)  
Image V3034-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V3034-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V3034SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name TNFS7/1026
Purity Protein G affinity chromatography
UniProt P32970
Localization Cell surface
Applications ELISA (order BSA/sodium azide-free format for coating) :
Functional studies (order BSA/sodium azide-free format) :
Flow cytometry : 1-2ug/10^6 cells
Immunofluorescence : 1-2ug/ml
Immunohistochemistry (Frozen) : 0.5-1ug/ml for 30 min at RT
Limitations This CD70 antibody is available for research use only.
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Description

It recognizes a protein of 30kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.

Application Notes

The concentration stated for each application is a general starting point. Optimal dilution of the CD70 antibody should be determined by the researcher.

Immunogen

Recombinant human protein was used as the immunogen for the CD70 antibody.

Storage

Store the CD70 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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