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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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CD5 (CD5) is a cell surface glycoprotein expressed on T lymphocytes and a subset of B cells, where it serves as a key marker in both normal immune function and disease. CD5 Antibody / Lymphoid Malignancy Marker Antibody is used to detect CD5 in the context of hematologic malignancies, where its expression is associated with specific disease subtypes and immune cell origins. CD5 antibody, also known as T cell surface glycoprotein CD5 antibody or LEU1 antibody, is widely used in studies of leukemia, lymphoma, and lymphoid disorders.
CD5 is consistently expressed on mature T cells, making it a reliable marker for identifying T cell-derived malignancies. In addition, its expression on certain B cell populations is a defining feature of diseases such as chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. This dual expression pattern makes CD5 antibody particularly valuable for distinguishing between different lymphoid malignancies and understanding their cellular origins.
In lymphoma research, CD5 expression is used to classify disease subtypes and to characterize tumor cell phenotype. The presence or absence of CD5 provides important biological context that can inform disease mechanisms and progression. CD5 antibody enables detection of these patterns, supporting studies focused on tumor biology, immune involvement, and disease heterogeneity within lymphoid cancers.
Beyond classification, CD5 is also relevant in studies of disease-associated signaling and immune dysregulation. Alterations in CD5 expression or function can influence signaling pathways that regulate lymphocyte behavior, contributing to tumor growth or immune evasion. CD5 antibody supports investigation of these processes by enabling detection of CD5 in experimental systems examining disease mechanisms and therapeutic response.
CD5 is also useful for studying the tumor microenvironment in hematologic malignancies, where interactions between malignant cells and surrounding immune cells play a critical role in disease progression. Detection of CD5-positive populations provides insight into these interactions and supports studies exploring immune-mediated aspects of cancer biology.
This antibody is suitable for detecting CD5 in research applications focused on lymphoid malignancies and hematologic disease. Its ability to identify CD5-positive populations supports studies of leukemia, lymphoma, and immune-related disorders.
Because CD5 is a key marker associated with lymphoid malignancies, CD5 antibody is widely used in studies of cancer biology, disease classification, and immune system dysfunction.
A full range of CD5 antibody reagents for immunohistochemistry, western blot, and flow cytometry is available on our CD5 Antibody collection page.
Optimal dilution of the CD5 Antibody / Lymphoid Malignancy Marker Antibody should be determined by the researcher.
A recombinant human protein fragment corresponding to the CD5 extracellular domain was used as the immunogen for the CD5 antibody.
Aliquot the CD5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
CD5 lymphoma marker antibody, CD5 leukemia marker antibody, CD5 hematologic malignancy antibody, CD5 CLL marker antibody, CD5 mantle cell lymphoma antibody
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