- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
CD5 Antibody / Inflammatory Response Regulation Marker Antibody [clone CLDA5-1] (V7018)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
V7018-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 100 ug | 559 | |
|
|
V7018-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 20 ug | 259 | |
|
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V7018SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
|
| Species Reactivity | Human |
| Format | Purified |
| Host | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, kappa |
| Clone Name | CLDA5-1 |
| Purity | Protein G affinity chromatography |
| Buffer | 1X PBS, pH 7.4 |
| Gene ID | 921 (Human) |
| Localization | Cell surface |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT |
| Limitations | This CD5 Antibody / Inflammatory Response Regulation Marker Antibody is available for research use only. |
|
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CD5 (CD5) is a transmembrane glycoprotein expressed on T lymphocytes and a subset of B cells, where it plays a role in regulating immune responses and inflammatory signaling. CD5 Antibody / Inflammatory Response Regulation Marker Antibody is used to detect CD5 in the context of inflammation, where it contributes to the modulation of immune activation and cytokine-driven responses. CD5 antibody, also known as T cell surface glycoprotein CD5 antibody or LEU1 antibody, is widely used in studies of inflammatory pathways and immune system regulation.
Inflammatory responses require precise control to ensure effective defense against pathogens while preventing excessive tissue damage. CD5 contributes to this balance by regulating signaling pathways that influence T cell activation and cytokine production. By modulating activation thresholds, CD5 helps limit excessive inflammatory responses and supports maintenance of immune homeostasis. CD5 antibody is therefore a valuable tool for studying mechanisms that control inflammation at the cellular level.
CD5-positive T lymphocytes are key contributors to inflammatory processes, particularly in contexts involving infection, autoimmune disease, and chronic inflammatory conditions. Detection of CD5 enables identification of these cells within tissues and experimental systems, supporting analysis of inflammatory cell populations and their functional states. CD5 antibody is frequently used to investigate how immune cells respond during inflammatory conditions and how signaling pathways are altered under these circumstances.
CD5 is also involved in regulating cytokine signaling pathways that control inflammatory responses. Its role in modulating signal strength influences how immune cells produce and respond to inflammatory mediators. Detection of CD5 provides insight into how lymphocytes coordinate inflammatory responses and maintain balance during immune activation.
In disease contexts, dysregulated inflammation is associated with a wide range of conditions including autoimmune disorders, cancer, and chronic inflammatory diseases. Altered CD5 expression or function may contribute to these processes by affecting signaling pathways that regulate immune responses. CD5 antibody supports research into these conditions by enabling detection of immune cells involved in inflammatory pathways and providing insight into mechanisms of immune dysregulation.
CD5 is also relevant in studies of tissue-specific inflammation, where immune cell localization and activation state influence disease progression. Detection of CD5 helps characterize the distribution of lymphocytes within inflamed tissues and supports studies of immune cell behavior in these environments.
This antibody is suitable for detecting CD5 in research applications focused on inflammatory response and immune regulation. Its ability to identify CD5-positive lymphocytes supports studies of inflammation, immune activation, cytokine signaling, and disease-associated changes in immune function.
Because CD5 plays a role in regulating inflammatory responses, CD5 antibody is widely used in studies of immune activation, cytokine-mediated signaling, and inflammation-related disease processes.
A full range of CD5 antibody reagents for immunohistochemistry, western blot, and flow cytometry is available on our CD5 Antibody collection page.
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD5 Antibody / Inflammatory Response Regulation Marker Antibody to be titered up or down for optimal performance.
Recombinant human protein was used as the immunogen for this CD5 antibody.
Store the CD5 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
CD5 inflammation regulator antibody, CD5 inflammatory response antibody, CD5 immune inflammation marker antibody, CD5 cytokine response antibody, CD5 inflammation signaling antibody
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