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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Recognizes a 67kDa transmembrane protein which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Note that this mAb is not suitable for frozen tissues.
Optimal dilution of the CD5 antibody should be determined by the researcher.
T cells activated with PHA were used as the immunogen for the CD5 antibody.
Store the CD5 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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