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Home >> Antibodies >> CD48 Antibody

CD48 Antibody (R32674)

  Catalog No Formulation Size Price (USD)  
Image R32674 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of human CEM cell lysate with CD48 antibody at 0.5ug/ml. Expected molecular weight 28 kDa (unmodified), up to 50 kDa (glycosylated).
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
UniProt P09326
Applications Western Blot : 0.5-1ug/ml
Limitations This CD48 antibody is available for research use only.
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Description

CD48 antigen (Cluster of Differentiation 48), also known as B-lymphocyte activation marker (BLAST-1) or signaling lymphocytic activation molecule 2 (SLAMF2), is a protein that in humans is encoded by the CD48 gene. This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Application Notes

Optimal dilution of the CD48 antibody should be determined by the researcher.

Immunogen

Amino acids E51-D146 from the human protein were used as the immunogen for the CD48 antibody.

Storage

After reconstitution, the CD48 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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