CD46 Antibody (R31975)

CD46 Antibody Human Colon Cancer IHC. Immunohistochemical staining of FFPE human colon cancer tissue demonstrates CD46 expression following heat-induced epitope retrieval in pH8 EDTA buffer. Strong brown DAB staining is observed predominantly along the cell membrane with accompanying cytoplasmic staining in malignant epithelial cells, consistent with the localization of membrane cofactor protein on the cell surface. Nuclei are counterstained blue with hematoxylin. This CD46 Antibody, also called Membrane Cofactor Protein Antibody, is suitable for studies of complement regulation, immune evasion, and colorectal cancer biology.

CD46 Antibody Human Prostate Cancer IHC. Immunohistochemical staining of FFPE human prostate cancer tissue demonstrates CD46 expression following heat-induced epitope retrieval in pH6 citrate buffer. Strong brown DAB staining is observed predominantly along the plasma membrane with accompanying cytoplasmic staining in malignant glandular epithelial cells, consistent with the localization of membrane cofactor protein as a complement regulatory cell surface glycoprotein. Nuclei are counterstained blue with hematoxylin. This CD46 Antibody, also called Membrane Cofactor Protein Antibody, is suitable for studies of complement regulation, tumor immune evasion, and prostate cancer biology.

CD46 Antibody Human Lung Cancer IHC. Immunohistochemical staining of FFPE human lung cancer tissue demonstrates CD46 expression following heat-induced epitope retrieval in pH8 EDTA buffer. Brown DAB staining is observed predominantly along the plasma membrane with additional cytoplasmic labeling in malignant epithelial cells, consistent with the localization of membrane cofactor protein as a complement regulatory cell surface glycoprotein. Nuclei are counterstained blue with hematoxylin. This CD46 Antibody, also called Membrane Cofactor Protein Antibody, is suitable for studies of complement regulation, tumor immune evasion, and lung cancer biology.

CD46 Antibody Mouse Testis IHC. Immunohistochemical staining of FFPE mouse testis tissue demonstrates CD46 expression following heat-induced epitope retrieval in pH8 EDTA buffer. Strong brown DAB staining is observed predominantly along the plasma membrane with additional cytoplasmic staining in seminiferous tubule cells, consistent with the localization of membrane cofactor protein on the cell surface. Nuclei are counterstained blue with hematoxylin. This CD46 Antibody, also called Membrane Cofactor Protein Antibody, is suitable for studies of complement regulation, reproductive biology, and cell surface glycoprotein expression.

CD46 Antibody T-47D Cell IF. Immunofluorescent staining of FFPE human T-47D cells demonstrates CD46 expression following heat-induced epitope retrieval in pH6 citrate buffer. CD46 is visualized in green with DAPI nuclear counterstaining in blue. Fluorescence is observed predominantly along the plasma membrane with additional cytoplasmic staining, consistent with the localization of membrane cofactor protein as a complement regulatory cell surface glycoprotein. This CD46 Antibody, also called Membrane Cofactor Protein Antibody, is suitable for immunofluorescence studies of complement regulation, breast cancer biology, and cell surface protein expression.

CD46 Antibody SiHa Cell IF. Immunofluorescent staining of SiHa cells demonstrates CD46 expression after enzyme-mediated antigen retrieval and labeling with a Fluoro488-conjugated secondary antibody (green), while nuclei are counterstained with DAPI (blue). Fluorescence is distributed predominantly along the plasma membrane with diffuse cytoplasmic staining, consistent with the localization of membrane cofactor protein as a complement regulatory cell surface glycoprotein. This CD46 Antibody, also called Membrane Cofactor Protein Antibody, is suitable for immunofluorescence studies of complement regulation, epithelial cell biology, and host-pathogen interactions.

CD46 Antibody HeLa Cell IF. Immunofluorescent staining of HeLa cells demonstrates CD46 expression after enzyme-mediated antigen retrieval and labeling with a Fluoro488-conjugated secondary antibody (green), while nuclei are counterstained with DAPI (blue). Fluorescence is observed predominantly along the plasma membrane with additional cytoplasmic staining, consistent with the localization of membrane cofactor protein as a cell surface complement regulatory glycoprotein. This CD46 Antibody, also called Membrane Cofactor Protein Antibody, is suitable for immunofluorescence studies of complement regulation, immune cell biology, and host-pathogen interactions.

CD46 Antibody Human Cancer Cell WB. Western blot demonstrates detection of CD46 in human HeLa and HepG2 cell lysates. A broad immunoreactive band is observed between approximately 50-70 kDa, higher than the predicted molecular weight of 44 kDa due to extensive glycosylation of membrane cofactor protein. The strong signal in both cancer cell lines is consistent with the widespread expression of CD46 on human nucleated cells and its role as a complement regulatory glycoprotein. GAPDH serves as the loading control. This CD46 Antibody, also called Membrane Cofactor Protein Antibody, is suitable for studies of complement regulation, immune cell biology, and host-pathogen interactions.

CD46 Antibody Human Cancer and Keratinocyte WB. Western blot demonstrates detection of CD46 in human A549 lung carcinoma, RT4 bladder carcinoma, and HaCaT keratinocyte cell lysates. A broad immunoreactive band is observed between approximately 50-70 kDa, higher than the predicted molecular weight of 44 kDa due to extensive N-linked and O-linked glycosylation of membrane cofactor protein. Variable electrophoretic mobility among the cell lines is consistent with differences in CD46 glycosylation and isoform expression. This CD46 Antibody, also called Membrane Cofactor Protein Antibody, is suitable for studies of complement regulation, immune responses, and cell surface glycoprotein expression.

CD46 Antibody Rat and Mouse Immune Tissue WB. Western blot demonstrates detection of CD46 in rat thymus, rat spleen, mouse thymus, and mouse spleen tissue lysates. A distinct immunoreactive band is observed at approximately 50 kDa in all samples, consistent with the glycosylated forms of membrane cofactor protein, which commonly migrate above the predicted molecular weights of 33-44 kDa. The consistent detection across lymphoid tissues from both species reflects the broad expression of CD46 in immune-associated organs. This CD46 Antibody, also called Membrane Cofactor Protein Antibody, is suitable for studies of complement regulation, immune cell biology, and host defense mechanisms across rodent tissues.