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- Email: info@nsjbio.com
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The ITGA2B gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [RefSeq]
Optimal dilution of the CD41 antibody should be determined by the researcher.
A synthetic peptide specific to human CD41 / ITGA2B was used as the immunogen for the CD41 antibody.
Store the CD41 antibody at -20oC.
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