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Home >> Antibodies >> CD4 Antibody

CD4 Antibody [clone RIV7] (V8208)

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  Catalog No Formulation Size Price (USD)  
Image V8208-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V8208-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V8208SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Flow cytometry staining of lymphocyte gated human PBM cells with CD4 antibody; Gray=isotype control, Red= CD4 antibody.
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Flow cytometry staining of lymphocyte gated human PBM cells with CD4 antibody; Gray=isotype control, Red= CD4 antibody.
SDS-PAGE analysis of purified, BSA-free CD4 antibody (clone RIV7) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a, kappa
Clone Name RIV7
Purity Protein G affinity chromatography
UniProt P06332
Localization Cell surface
Applications Functional Studies (order BSA/azide-free format) :
Flow cytometry : 1-2ug/10^6 cells in 0.1ml
Immunofluorescence : 1-2ug/ml
Limitations This CD4 antibody is available for research use only.
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Description

Recognizes a protein of 55kDa, identified as CD4. It is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Application Notes

Optimal dilution of the CD4 antibody should be determined by the researcher.

Immunogen

Human peripheral lymphocytes were used as the immunogen for the CD4 antibody.

Storage

Store the CD4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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