- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
CD38 Antibody for IF / CD38 Immunofluorescence Antibody (F48288)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
F48288-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 439 | |
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F48288-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 205 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Predicted Reactivity | Primate |
| Format | Purified |
| Host | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Purified |
| UniProt | P28907 |
| Applications | Western Blot : 1:1000-4000 IHC (Paraffin) : 1:50-1:100 Immunofluorescence : 1:10-1:50 Flow Cytometry : 1:10-1:50 |
| Limitations | This CD38 Antibody for IF / CD38 Immunofluorescence Antibody is available for research use only. |
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CD38 (CD38) is a type II transmembrane glycoprotein with ectoenzyme activity that regulates NAD metabolism and calcium signaling, and is prominently expressed on the surface of plasma cells, activated T and B lymphocytes, natural killer cells, and subsets of myeloid cells. Its distribution at the plasma membrane, combined with intracellular trafficking and compartmentalization, makes CD38 particularly well suited for fluorescence-based imaging approaches that resolve both cell surface localization and subcellular organization.
CD38 Antibody for IF / CD38 Immunofluorescence Antibody is optimized for fluorescence detection of CD38, enabling high-resolution visualization of its spatial distribution in fixed cells and tissue sections. CD38 antibody, also known as cyclic ADP-ribose hydrolase antibody or ADPRC1 antibody, is widely used in immunofluorescence assays to examine immune cell architecture, activation states, and spatial relationships within complex cellular environments.
In immunofluorescence applications, CD38 staining typically appears as a strong membrane-associated signal outlining the cell surface, often accompanied by punctate or diffuse cytoplasmic fluorescence reflecting intracellular pools and vesicular trafficking. This dual localization pattern allows clear delineation of cell boundaries while also providing insight into intracellular distribution, making CD38 particularly useful for studying membrane dynamics and protein trafficking in immune cells.
The fluorescence-based detection of CD38 enables precise visualization of individual cells within densely populated samples, where membrane signal helps distinguish closely adjacent cells and supports analysis of cell-cell interactions. When combined with nuclear counterstains such as DAPI, CD38 staining provides strong contrast between membrane, cytoplasmic, and nuclear compartments, enhancing interpretation of cellular morphology and organization.
CD38 is frequently used in co-localization studies with additional immune or lineage markers, allowing simultaneous visualization of multiple targets within the same sample. This enables identification of specific cell subsets and functional states based on overlapping or complementary expression patterns. The ability to integrate CD38 into multicolor fluorescence panels makes it a valuable component of imaging-based immune profiling strategies.
The use of a rabbit polyclonal CD38 antibody provides broad epitope recognition, supporting strong fluorescence signal intensity and reliable detection across cells with variable antigen expression. This can improve visualization of both high-expressing plasma cells and lower-expressing activated lymphocyte populations within heterogeneous samples, ensuring consistent signal across a range of expression levels.
Immunofluorescence detection of CD38 is well suited for both cultured cells and tissue-derived specimens, where it enables detailed analysis of spatial distribution, membrane organization, and intracellular localization. Compared to chromogenic detection methods, fluorescence imaging provides enhanced resolution and multiplexing capability, allowing CD38-positive cells to be studied within the broader context of cellular networks and tissue architecture.
CD38 Immunofluorescence Antibody is therefore a powerful tool for high-resolution imaging, co-localization analysis, and spatial characterization of immune cell populations, supporting detailed investigation of plasma cells and activated lymphocytes within complex biological systems.
This antibody is part of our CD38 antibody collection, which includes application-specific formats for immunohistochemistry, flow cytometry, western blot, and immunofluorescence research.
Titration of the CD38 Antibody for IF / CD38 Immunofluorescence Antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 241-270 from the human protein was used as the immunogen for this CD38 antibody.
Aliquot the CD38 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
CD38 immunofluorescence antibody, CD38 IF antibody, CD38 cell surface marker antibody, CD38 plasma cell marker antibody, CD38 immune activation marker antibody
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