- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
CD37 Antibody [clone IPO-24] (V3006)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
V3006-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 100 ug | 539 | |
|
|
V3006-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 20 ug | 249 | |
|
|
V3006SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 539 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG2b, kappa |
| Clone Name | IPO-24 |
| Purity | Protein G affinity chromatography |
| UniProt | P11049 |
| Localization | Cell surface |
| Applications | Functional Studies (order BSA/sodium Azide-free Format) : Flow Cytometry : 0.5-1ug/10^6 cells Immunofluorescence : 0.5-1ug/ml |
| Limitations | This CD37 antibody is available for research use only. |
|
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CD37 antibody clone IPO-24 is a monoclonal antibody specific for CD37, a member of the tetraspanin family expressed primarily on mature B lymphocytes and dendritic cells. CD37 organizes membrane microdomains and modulates signaling pathways that influence survival, proliferation, and immune interactions. NSJ Bioreagents provides this antibody for immunology, oncology, and hematology research.
The antibody produces strong membranous staining in B cells and dendritic cells. In immunology, CD37 detection supports studies of B cell biology, antigen presentation, and immune regulation. CD37 has been implicated in antibody responses and in the regulation of T cellâB cell interactions.
In hematology, CD37 is an important marker of B cell lineage. The antibody has been used in research to classify B cell lymphomas and leukemias, where CD37 expression provides diagnostic and prognostic information.
In oncology, CD37 antibody clone IPO-24 has been applied to studies of therapeutic targeting. Because CD37 is selectively expressed on mature B cells and their malignancies, it has been investigated as a target for monoclonal antibodies and antibody-drug conjugates. This reagent supports both preclinical and translational research into CD37-directed therapies.
CD37 also participates in cell adhesion and migration, and its detection has been applied to studies of lymphoid tissue organization and immune signaling networks. By enabling reproducible detection, this antibody provides a versatile tool across multiple disciplines.
Validated in tissue-based and cell-based systems, the antibody provides reliable staining with minimal background. Alternate names include tetraspanin 26 antibody, B cell surface marker antibody, and lymphoid membrane protein antibody.
Optimal dilution of the CD37 antibody should be determined by the researcher.
Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the CD37 antibody.
Store the CD37 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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