- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
CD34 Antibody [clone ICO-115] (V2065)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
V2065-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 100 ug | 539 | |
|
|
V2065-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 20 ug | 249 | |
|
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V2065SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 539 |
| Species Reactivity | Human, Rat |
| Format | Purified |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, kappa |
| Clone Name | ICO-115 |
| Purity | Protein G affinity chromatography |
| Buffer | 1X PBS, pH 7.4 |
| Gene ID | 947 |
| Localization | Cell surface |
| Applications | ELISA (order BSA/sodium Azide-free Format For Coating) : Flow Cytometry : 1-2ug/10^6 cells Immunofluorescence : 0.5-1ug/ml |
| Limitations | This CD34 antibody is available for research use only. |
|
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CD34 antibody clone ICO-115 is a monoclonal antibody that detects CD34, a transmembrane glycoprotein present on hematopoietic stem and progenitor cells as well as vascular endothelial cells. CD34 plays a central role in hematopoiesis, angiogenesis, and progenitor cell biology. Because of its broad applications, it is one of the most commonly used markers for identifying stem cells and endothelial cells in research and diagnostic pathology. NSJ Bioreagents provides CD34 antibody as a reliable reagent for stem cell and vascular studies.
The antibody shows strong membranous staining on hematopoietic precursors in bone marrow and endothelial cells in vascular tissues. In stem cell research, clone ICO-115 has been widely applied to isolate and characterize hematopoietic progenitors and to monitor stem cell engraftment in transplantation studies.
In vascular biology, CD34 antibody labels endothelial cells and reveals vascular architecture. Its application supports research into angiogenesis, wound healing, and cardiovascular disease. By providing reliable detection of vascular endothelium, this antibody helps clarify processes of vessel formation and remodeling.
In oncology, the antibody is frequently used to evaluate tumor angiogenesis, where blood vessel density and structure provide prognostic information. Clone ICO-115 is also applied in identifying vascular tumors and distinguishing them from other malignancies.
Validated in tissue-based and cell-based systems, the antibody produces strong and consistent results. Alternate names include hematopoietic progenitor marker antibody, vascular endothelial cell antibody, and stem cell marker CD34 antibody.
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.
Blast cells from a chronic myeloid leukemia patient were used as the immunogen for this CD34 antibody.
Store the CD34 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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