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Home >> Antibodies >> CD30 Antibody

CD30 Antibody (R30131)

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  Catalog No Formulation Size Price (USD)  
Image R30131 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of CD30 antibody and Lane 1: HeLa; 2: 293T; 3: Jurkat; Predicted molecular weight: 53-120 kDa depending on glycosylation level.
Western blot testing of CD30 antibody and Lane 1: HeLa; 2: 293T; 3: Jurkat; Predicted molecular weight: 53-120 kDa depending on glycosylation level.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Gene ID 943
Applications Western blot : 0.5-1ug/ml
Limitations This CD30 antibody is available for research use only.
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Description

CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. This gene is mapped to 1p36.22. Expression is seen in embryonal carcinoma but not in seminoma and is thus a useful marker in distinguishing between these germ cell tumors. CD30 mast cell activation represents an IgE-independent activation pathway, which is important for understanding cutaneous inflammation associated with mast cells. In addition to those, CD30 is also associated with anaplastic large cell lymphoma.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the CD30 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Human partial recombinant protein (AA 322-595) was used as the immunogen for this CD30 antibody.

Storage

After reconstitution, the CD30 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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