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- Tel: 858.663.9055
- Email: info@nsjbio.com
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Titration of the CD30 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 294-321 from the human protein was used as the immunogen for this CD30 antibody.
Aliquot the CD30 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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