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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Recognizes a glycoprotein of 110kDa, identified as CD26 (Workshop VI; Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this mAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.
Explore our CD26 Antibody / DPP4 Antibody - Broad T Cell Activation and Enzyme Marker for a comprehensive overview of CD26 expression, function, and related antibody tools.
Optimal dilution of the CD26 antibody should be determined by the researcher.
A human T cell clone was used as the immunogen for the CD26 antibody.
Store the CD26 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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