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Home >> Antibodies >> CD25 Antibody

CD25 Antibody [clone 7G7B6] (F53547)

  Catalog No Formulation Size Price (USD)  
Image F53547-0.1ML In ascites with 0.09% sodium azide 0.1 ml 399
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CD25 antibody western blot analysis in Jurkat lysate
Availability 1-3 business days
Species Reactivity Human
Format Ascites
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a
Clone Name 7G7B6
Purity Ascites
UniProt P01589
Applications Western blot : 1:100-1:800
Limitations This CD25 antibody is available for research use only.
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Description

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.

Application Notes

Titration of the CD25 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A purified His-tagged recombinant protein fragment was used to produced this CD25 antibody.

Storage

Aliquot the CD25 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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