CD22 Antibody / BL-CAM [clone CBO-3] (RQ8901)

Description

CD22 (BL-CAM) is a B cell-specific transmembrane glycoprotein that functions as an inhibitory receptor, regulating B cell receptor (BCR) signaling. It belongs to the immunoglobulin superfamily and modulates B cell activation thresholds, helping maintain immune tolerance and prevent overactivation of the immune response.

CD22 is primarily expressed on mature B cells and plays a role in B cell survival, adhesion, and migration within lymphoid tissues. Altered CD22 expression or function has been associated with autoimmune diseases and B cell malignancies, making it an important biomarker and therapeutic target in immunology and oncology research.

Using a high-quality CD22 antibody enables sensitive detection in applications such as flow cytometry, immunohistochemistry, and western blot. A CD22 antibody from NSJ Bioreagents ensures reproducibility and accuracy for studies in B cell biology, immune regulation, and cancer research. Selecting the right CD22 antibody is critical for generating consistent and reliable experimental results.

Application Notes

Optimal dilution of the CD22 antibody should be determined by the researcher.

Immunogen

A peptide sequence specific to CD22 was used as the immunogen for the CD22 antibody.

Storage

After reconstitution, the CD22 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.