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Home >> Antibodies >> CD2 Antibody

CD2 Antibody [clone RPA-2.10] (V8198)

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  Catalog No Formulation Size Price (USD)  
Image V8198-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V8198-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V8198SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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SDS-PAGE analysis of purified, BSA-free CD2 antibody (clone RPA-2.10) as confirmation of integrity and purity.
SDS-PAGE analysis of purified, BSA-free CD2 antibody (clone RPA-2.10) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name RPA-2.10
Purity Protein G affinity chromatography
UniProt P06729
Applications Functional Studies (order BSA/azide-free format) :
Flow cytometry : 1-2ug/10^6 cells in 0.1ml
Limitations This CD2 antibody is available for research use only.
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Description

CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

Application Notes

Optimal dilution of the CD2 antibody should be determined by the researcher.

Immunogen

A recombinant full-length human CD2 protein was used as the immunogen for the CD2 antibody.

Storage

Store the CD2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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