CD163L1 Antibody (F43408)

CD163L1 Antibody Human Lymph Node IHC. Immunohistochemistry staining of FFPE human lymph node tissue using CD163L1 antibody demonstrates widespread cytoplasmic and membranous HRP-DAB brown staining within lymphoid cell populations and scattered macrophage-like cells throughout the nodal architecture. The staining pattern is consistent with expression of CD163 Like 1 / CD163L1, a scavenger receptor family protein associated with monocyte-macrophage lineage cells and innate immune regulation. Positive staining is observed within densely cellular lymphoid regions, supporting the utility of CD163L1 as a marker for studies of immune cell heterogeneity, tissue-resident myeloid populations, and lymphoid tissue immune surveillance. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

CD163L1 Antibody Human Spleen IHC. Immunohistochemistry staining of FFPE human spleen tissue using CD163L1 antibody demonstrates widespread cytoplasmic and membranous HRP-DAB brown staining throughout densely packed immune cell populations within the splenic white pulp. The staining pattern is consistent with expression of CD163 Like 1 / CD163L1, a scavenger receptor family protein associated with monocyte-macrophage lineage cells and innate immune regulation. Robust staining within lymphoid-rich regions supports the utility of CD163L1 as a marker for studies of immune cell specialization, macrophage-associated biology, and maintenance of splenic immune homeostasis. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

CD163L1 Antibody U-2 OS WB. Western blot analysis of human U-2 OS cell lysate using CD163L1 antibody detects a prominent band at approximately 160-180 kDa, consistent with CD163 Like 1 / CD163L1. The observed molecular weight is higher than the calculated molecular weight predicted from the amino acid sequence, which is expected for heavily glycosylated scavenger receptor family proteins. CD163L1 is a transmembrane scavenger receptor cysteine-rich family member associated with monocyte-macrophage biology, innate immune regulation, and receptor-mediated cellular interactions. The detected signal supports expression of CD163L1 in U-2 OS cells and is consistent with the migration characteristics reported for glycosylated cell-surface receptors.