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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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CD163L1 Antibody specifically detects CD163L1 (CD163 molecule-like 1), also known as scavenger receptor cysteine-rich type 1 protein M160 or CD163B, a 1,453 amino acid protein that belongs to the scavenger receptor cysteine-rich (SRCR) superfamily. Members of the SRCR family contain SRCR domains which are used to influence ligand binding and protein-protein interaction and are found in cells of the immune system where they exist as membrane-anchored or secreted proteins. Containing 12 SRCR domains, CD163L1 undergoes alternative splicing events to produce 3 isoforms. CD163L1 isoforms 1 and 2 are single-pass type I membrane proteins, unlike isoform 3, which is a secreted protein. CD163L1 isoform 1 is abundantly expressed in lymph node, spleen, thymus and fetal liver, and isoform 2 is found exclusively in spleen. The gene encoding CD163L1 maps to human chromosome 12p13.31.
Researchers investigating CD163 Like 1 function, macrophage scavenger receptors, and innate immune cell populations may also wish to explore our CD163L1 Antibody page highlighting the role of this scavenger receptor family protein in monocyte and macrophage biology.
Optimal dilution of the CD163L1 antibody should be determined by the researcher.
A recombinant fragment of human CD163L1 protein was used as the immunogen for the CD163L1 antibody.
Aliquot the CD163L1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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