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Home >> Antibodies >> Cd16 Antibody

Cd16 Antibody (RQ6092)

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  Catalog No Formulation Size Price (USD)  
Image RQ6092 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of mouse thymus lysate with Cd16 antibody. Expected molecular weight: 30-70 kDa depending on the level of glycosylation.
Western blot testing of mouse thymus lysate with Cd16 antibody. Expected molecular weight: 30-70 kDa depending on the level of glycosylation.
Availability 1-3 business days
Species Reactivity Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt P08508
Applications Western blot : 1-2ug/ml
Limitations This Cd16 antibody is available for research use only.
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Description

Low affinity immunoglobulin gamma Fc region receptor III-A is a protein that in humans is encoded by the FCGR3A gene. This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Application Notes

Optimal dilution of the Cd16 antibody should be determined by the researcher.

Immunogen

Amino acids ALYFYVRRNLQTPREYWRK from the mouse protein were used as the immunogen for the Cd16 antibody.

Storage

After reconstitution, the Cd16 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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