- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
CD14 Antibody LPSR/7738 / Mouse Monoclonal [clone LPSR/7738] (V5447)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
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V5447-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 559 | |
|
|
V5447-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 259 | |
|
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V5447SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
| Species Reactivity | Human |
| Format | Purified |
| Host | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG2, kappa |
| Clone Name | LPSR/7738 |
| Purity | Protein A/G affinity |
| UniProt | P08571 |
| RRID | AB_3756924 |
| Localization | Cell membrane |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml |
| Limitations | This CD14 Antibody LPSR/7738 is available for research use only. |
|
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CD14 Antibody LPSR/7738 recognizes a protein of 55kDa, identified as CD14 (also known lipopolysaccharide receptor). CD14 is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation.
For an alternative antibody targeting the same monocyte and macrophage surface marker, see our CD14 Antibody LPSR/2385, a mouse monoclonal antibody featuring IHC, western blot, flow cytometry, and protein microarray validation.
Optimal dilution of the CD14 Antibody LPSR/7738 should be determined by the researcher.
A recombinant fragment of human CD14 protein (within amino acids 1-200) was used as the immunogen for the CD14 Antibody LPSR/7738.
Aliquot the CD14 Antibody LPSR/7738 and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
CD14 antibody, LPS Receptor antibody, Lipopolysaccharide Receptor antibody, Monocyte Marker antibody, Macrophage Marker antibody, Monocyte Differentiation Antigen CD14 antibody, Cluster of Differentiation 14 antibody
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