CD135 Antibody / Hematopoietic Progenitor Marker (RQ7227)

CD135 Antibody Spleen IHC. Immunohistochemistry analysis of FFPE human spleen tissue stained with CD135 antibody. Distinct membranous and cytoplasmic HRP-DAB brown staining is observed within lymphoid cell populations, consistent with the expected expression profile of Fms-like tyrosine kinase 3 / FLT3/CD135, a class III receptor tyrosine kinase involved in hematopoietic progenitor regulation, cytokine-responsive signaling, and immune-associated cellular development pathways. Tissue sections underwent HIER using pH 8 EDTA buffer prior to immunostaining.

CD135 Antibody HCCP WB. Western blot analysis of human HCCP cell lysate using CD135 antibody. Major bands are detected between approximately 113-180 kDa, consistent with the expected molecular weight range of glycosylated Fms-like tyrosine kinase 3 / FLT3/CD135 receptor species. The observed higher molecular weight pattern is compatible with extensive glycosylation commonly associated with transmembrane receptor tyrosine kinases involved in hematopoietic signaling and cytokine-responsive cellular regulation pathways.