- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
CD133 Antibody / PROM1 [clone 6H10-F1-C11] (F54026)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54026-0.1ML | In PBS with 50% glycerol, 0.1mg/ml BSA and 0.02% sodium azide | 0.1 ml | 399 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG2a |
| Clone Name | 6H10-F1-C11 |
| Purity | Protein G affinity |
| UniProt | O43490 |
| Applications | Western blot : 1:1000 |
| Limitations | This CD133 antibody is available for research use only. |
|
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CD133/PROM1/Prominin-1 may play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner. [UniProt]
The stated application concentrations are suggested starting points. Titration of the CD133 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A human recombinant partial protein was used as the immunogen for this CD133 antibody.
Store the CD133 antibody at -20oC.
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