- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
CD11b Antibody / MAC-1 / ITGAM [clone BCG-9] (RQ5357)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ5357 | Antibody in PBS with 0.02% sodium azide and 50% glycerol | 100 ul | 429 |
| Availability | 1-2 weeks |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | BCG-9 |
| Purity | Affinity purified |
| UniProt | P11215 |
| Applications | Western blot : 1:500-1:2000 Immunohistochemistry (FFPE) : 1:50-1:200 |
| Limitations | This CD11b antibody is available for research use only. |
|
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The ITGAM gene encodes the integrin alpha M chain, also called CD11b and MAC-1. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [RefSeq]
Optimal dilution of the CD11b antibody should be determined by the researcher.
A synthetic peptide specific to human CD11b / ITGAM was used as the immunogen for the CD11b antibody.
Store the CD11b antibody at -20oC.
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