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Home >> Antibodies >> CD11b Antibody / MAC-1

CD11b Antibody / MAC-1 [clone CDLA11b-1] (V8135)

  Catalog No Formulation Size Price (USD)  
Image V8135-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V8135-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V8135SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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IHC staining of FFPE human spleen with CD11b antibody (clone CDLA11b-1). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name CDLA11b-1
Purity Protein G affinity chromatography
UniProt P11215
Localization Cell membrane, cytoplasm
Applications Western blot : 1-2ug/ml
Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This CD11b antibody is available for research use only.
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Description

Integrin ITGAM/ITGB2/CD11b/MAC-1 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. [UniProt]

Application Notes

The stated application concentrations are suggested starting points. Titration of the CD11b antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Amino acids 941-1074 were used as the immunogen for this CD11b antibody.

Storage

Store the CD11b antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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