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Home >> Antibodies >> CD117 Antibody / c-Kit

CD117 Antibody / c-Kit [clone KIT/2669] (V7906)

  Catalog No Formulation Size Price (USD)  
Image V7906-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V7906-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V7906SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated
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Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using CD117 antibody (clone KIT/2669). These results demonstrate the foremost specificity of the KIT/2669 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
SDS-PAGE analysis of purified, BSA-free CD117 antibody (clone KIT/2669) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name KIT/2669
Purity Protein G affinity chromatography
UniProt P10721
Localization Cell surface, cytoplasmic
Applications ELISA (order BSA-free format for coating) :
Limitations This CD117 antibody is available for research use only.
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Description

This MAb recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.

Application Notes

Optimal dilution of the CD117 antibody should be determined by the researcher.

Immunogen

Recombinant human full length protein was used as the immunogen for the CD117 antibody.

Storage

Store the CD117 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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