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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This MAb inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells.
Optimal dilution of the CD106 antibody should be determined by the researcher.
Recombinant full-length human protein was used as the immunogen for the CD106 antibody.
Store the CD106 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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