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Home >> Antibodies >> CD104 Antibody / Integrin beta 4 / ITGB4

CD104 Antibody / Integrin beta 4 / ITGB4 [clone AAFE-9] (RQ5468)

  Catalog No Formulation Size Price (USD)  
Image RQ5468 Antibody in PBS with 0.02% sodium azide and 50% glycerol 100 ul 429
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Western blot testing of 1) human SW480 and 2) mouse spleen lysate with CD104 antibody. Predicted molecular weight ~200 kDa.
Availability 1-2 weeks
Species Reactivity Human, Mouse
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name AAFE-9
Purity Affinity purified
UniProt P16144
Applications Western blot : 1:500-1:2000
Limitations This CD104 antibody is available for research use only.
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Description

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. The ITGB4 gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. [RefSeq]

Application Notes

Optimal dilution of the CD104 antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Integrin beta 4 / ITGB4 was used as the immunogen for the CD104 antibody.

Storage

Store the CD104 antibody at -20oC.

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