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Home >> Antibodies >> CCR1 Antibody

CCR1 Antibody (R32913)

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  Catalog No Formulation Size Price (USD)  
Image R32913 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of rat PC-12 cell lysate with CCR1 antibody at 0.5ug/ml. Predicted molecular weight 40-45 kDa.
Western blot testing of rat PC-12 cell lysate with CCR1 antibody at 0.5ug/ml. Predicted molecular weight 40-45 kDa.
Availability 1-3 business days
Species Reactivity Rat
Predicted Reactivity Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
UniProt P51675
Localization Cytoplasmic, membranous
Applications Western Blot : 0.5-1ug/ml
Limitations This CCR1 antibody is available for research use only.
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Description

C-C chemokine receptor type 1 is a protein that in humans is encoded by the CCR1 gene. This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite.

Application Notes

Optimal dilution of the CCR1 antibody should be determined by the researcher.

Immunogen

A recombinant mouse protein corresponding to amino acids A168-T339 was used as the immunogen for the CCR1 antibody.

Storage

After reconstitution, the CCR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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