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Home >> Antibodies >> Ccl21 Antibody

Ccl21 Antibody (RQ6833)

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  Catalog No Formulation Size Price (USD)  
Image RQ6833 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Flow cytometry testing of rat C6 cells with Ccl21 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Ccl21 antibody.
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Flow cytometry testing of rat C6 cells with Ccl21 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Ccl21 antibody.
Western blot testing of 1) rat thymus, 2) mouse spleen and 3) mouse ANA-1 cell lysate with Ccl21 antibody. Predicted molecular weight ~15 kDa.
Availability 1-3 business days
Species Reactivity Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q5RJN3
Applications Western blot : 1-2ug/ml
Flow cytometry : 1-3ug/million cells
Direct ELISA : 0.1-0.5ug/ml
Limitations This Ccl21 antibody is available for research use only.
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    Reactivity : Human

Description

Chemokine (C-C motif) ligand 21 (CCL21) is a small cytokine belonging to the CC chemokine family. This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).

Application Notes

Optimal dilution of the Ccl21 antibody should be determined by the researcher.

Immunogen

Recombinant rat protein (amino acids S24-Q133) was used as the immunogen for the Ccl21 antibody.

Storage

After reconstitution, the Ccl21 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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