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Home >> Antibodies >> CB2 Antibody / Cannabinoid Receptor 2

CB2 Antibody / Cannabinoid Receptor 2 (F40838)

  Catalog No Formulation Size Price (USD)  
Image F40838-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 439
Image
F40838-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 205
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CB2 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma.
IHC analysis of FFPE human brain using CB2 antibody at 1:25.
IHC analysis of FFPE rat brain using CB2 antibody at 1:25.
CB2 antibody western blot analysis in A431 lysate. Predicted molecular weight ~38 kDa.
Flow cytometric analysis of Jurkat cells using CB2 antibody (green) compared to an isotype control of rabbit Ig (blue). Ab was diluted at 1:25 dilution. An Alexa Fluor 488 goat anti-rabbit lgG was used as the secondary Ab.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Host Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P34972
Applications Western Blot : 1:1000
IHC (Paraffin) : 1:10-1:50
Flow Cytometry : 1:10-1:50
Limitations This CB2 antibody is available for research use only.
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Description

The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. Cannabinoid receptor 2 and cannabinoid receptor 1 (brain) (CNR1) have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.

Application Notes

Titration of the CB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 329-356 from the human protein was used as the immunogen for this CB2 antibody.

Storage

Aliquot the CB2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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