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Home >> Antibodies >> CaV1.3 Antibody

CaV1.3 Antibody (R31742)

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Image R31742 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of CaV1.3 antibody and Lane 1: rat brain; 2: mouse brain lysate. Predicted molecular weight: ~245 kDa.
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Western blot testing of CaV1.3 antibody and Lane 1: rat brain; 2: mouse brain lysate. Predicted molecular weight: ~245 kDa.
Flow cytometry testing of human U-87 MG cells with CaV1.3 antibody at 1ug/10^6 cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= CaV1.3 antibody.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Gene ID 776
Applications Western blot : 0.5-1ug/ml
Flow Cytometry : 1-3ug/10^6 cells
Limitations This CaV1.3 antibody is available for research use only.
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  • Applications : WB
    Reactivity : Human, Mouse, Rat

Description

CACNA1D is also known as PASNA, SANDD or Cav1.3. Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene.

Application Notes

Variations in secondary/substrate sensitivities and test protocols may require the CaV1.3 antibody to be titrated for optimal performance.

Immunogen

Human partial recombinant protein (AA 1-180) was used as the immunogen for this CaV1.3 antibody.

Storage

After reconstitution, the CaV1.3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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