• Tel: 858.663.9055
  • SeparatorEmail: info@nsjbio.com
  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Order
Home >> Antibodies >> Caspase-2 Antibody

Caspase-2 Antibody (R30278)

NSJ bio Image Pdf Image
  Catalog No Formulation Size Price (USD)  
Image R30278 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
Bulk quote request
Western blot testing of Caspase-2 antibody and Lane 1: human CCRF-CEM; 2: human SMMC-7721 cell lysate. Predicted molecular weight: ~47 kDa (full), ~31 kDa (large+small subunit), ~11 kDa (small subunit).
Western blot testing of Caspase-2 antibody and Lane 1: human CCRF-CEM; 2: human SMMC-7721 cell lysate. Predicted molecular weight: ~47 kDa (full), ~31 kDa (large+small subunit), ~11 kDa (small subunit).
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt P42575
Applications Western blot : 0.5-1ug/ml
Limitations This Caspase-2 antibody is available for research use only.
Review this product on BioCompare and get a $20 Amazon gift card

Related Products

  • Applications : WB, IHC-P, Direct ELISA
    Reactivity : Human, Mouse, Rat
  • Applications : WB
    Reactivity : Human, Mouse, Rat
  • Applications : WB, IHC, FACS, ELISA
    Reactivity : Human

Description

Caspase-2/CASP2, which is involved in stress-induced apoptosis, is recruited into a large protein complex, the molecular composition of which remains elusive. Activation of Caspase-2 occurs in a complex that contains the death domain-containing protein PIDD, whose expression is induced by p53, and the adaptor protein RAIDD. Increased PIDD expression resulted in spontaneous activation of Caspase-2 and sensitization to apoptosis by genotoxic stimuli. CASP2 acts both as a positive and negative cell death effector, depending upon cell lineage and stage of development.

Application Notes

The stated application concentrations are suggested starting points. Titration of the Caspase-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Amino acids 417-439 (REGYAPGTEFHRCKEMSEYCSTL) were used as the immunogen for this Caspase-2 antibody (100% homologous in human, mouse and rat). This sequence is from the small subunit.

Storage

After reconstitution, the Caspase-2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Related Products

   1.   View all Caspase antibodies

   2.   View all Caspase-2 antibodies

Cross
Bulk Quote Request Form
Name*:
Organization*:
Email*:
Phone Number*:
Catalog No.*:
Comments and Specifics(amount, formulation, etc.)*:
Validation code: Captchapackage Image


Can't read the image? click here to refresh.
    *required field

Your bulk quote request has been submitted successfully!

Please contact us if you have any questions.