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Home >> Antibodies >> Carboxypeptidase M Antibody / CPM

Carboxypeptidase M Antibody / CPM (R32609)

  Catalog No Formulation Size Price (USD)  
Image R32609 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of human HepG2 cell lysate with Carboxypeptidase M antibody at 0.5ug/ml. Expected molecular weight: 51-65 kDa depending on glycosylation level.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt P14384
Applications Western blot : 0.1-0.5ug/ml
Limitations This Carboxypeptidase M antibody is available for research use only.
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Description

CPM, mapped to 12q15, is known as Carboxypeptidase M. The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.

Application Notes

Optimal dilution of the Carboxypeptidase M antibody should be determined by the researcher.

Immunogen

Amino acids 286-316 (KYPREEKLPSFWNNNKASLIEYIKQVHLGVK-human) were used as the immunogen for the Carboxypeptidase M antibody.

Storage

After reconstitution, the Carboxypeptidase M antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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