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Home >> Antibodies >> Carbonic Anhydrase VIII Antibody / CA8

Carbonic Anhydrase VIII Antibody / CA8 [clone CA8/6572] (V8822)

  Catalog No Formulation Size Price (USD)  
Image V8822-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V8822-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V8822SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated
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IHC staining of FFPE human brain tissue with Carbonic Anhydrase VIII antibody (clone CA8/6572). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free Carbonic Anhydrase VIII antibody (CA8/6572) as confirmation of integrity and purity.
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using Carbonic Anhydrase VIII antibody (clone CA8/6572). These results demonstrate the foremost specificity of the CA8/6572 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a, kappa
Clone Name CA8/6572
Purity Protein A/G affinity
UniProt P35219
Localization Cytoplasm, Cell surface
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This Carbonic Anhydrase VIII antibody is available for research use only.
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Description

Carbonic anhydrase-related protein is an protein that in humans is encoded by the CA8 gene. The CA8 protein lacks the catalytic activity of other carbonic anhydrase enzymes. A rare, autosomal recessive form of cerebellar ataxia known as cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CAMRQ3) is caused by mutations in the CA8 gene. [Wiki]

Application Notes

Optimal dilution of the Carbonic Anhydrase VIII antibody should be determined by the researcher.

Immunogen

Recombinant full-length human Carbonic Anhydrase VIII/CA8 protein was used as the immunogen for the Carbonic Anhydrase VIII antibody.

Storage

Aliquot the Carbonic Anhydrase VIII antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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