- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
CalDAG-GEFI Antibody / RASGRP2 (F54641)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54641-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
|
F54641-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity purified |
| UniProt | Q7LDG7 |
| Localization | Cytoplasmic |
| Applications | Immunofluorescence : 1:25 Immunohistochemistry (FFPE) : 1:25 Western blot : 1:500-1:2000 |
| Limitations | This CalDAG-GEFI antibody is available for research use only. |
|
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The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.
The stated application concentrations are suggested starting points. Titration of the CalDAG-GEFI antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 7-34 from the human protein was used as the immunogen for the CalDAG-GEFI antibody.
Aliquot the CalDAG-GEFI antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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