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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Cadherin 17, also known as HPT1 or CDH16 is a protein that in humans is encoded by the CDH17 gene. By somatic cell hybrid analysis and fluorescence in situ hybridization, CDH17 gene is mapped to 8q22.1. This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine.
Learn more about CDH17 expression, epithelial cell adhesion, tissue organization, and gastrointestinal epithelial biology on our Cadherin 17 Antibody / Epithelial Cell Adhesion Protein Antibody page.
The stated application concentrations are suggested starting points. Titration of the Cadherin 17 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Amino acids 686-699 (LIFEATDDDQHLFR-human) were used as the immunogen for this Cadherin 17 antibody.
After reconstitution, the Cadherin 17 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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