Cadherin 1 Antibody / Adhesion Signaling Integration Antibody [clone CDH1/4585] (V9299)

Cadherin 1 Antibody Skin IHC. Immunohistochemistry analysis of Cadherin 1 / CDH1 expression in FFPE human skin using clone CDH1/4585 antibody, showing strong membranous HRP-DAB brown staining in stratified epithelial cells of the epidermis with clear cell-cell junction localization, while underlying dermal tissue remains largely negative. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing. Signal highlights epithelial organization and adhesion-associated signaling within the epidermis.

IHC staining of FFPE human skin with Cadherin 1 antibody (clone CDH1/4585). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

Cadherin 1 Antibody Human Kidney IHC. Immunohistochemistry analysis of Cadherin 1 / CDH1 expression in FFPE human kidney tissue using clone CDH1/4585 antibody, showing membranous HRP-DAB brown staining in epithelial cells lining renal tubules with clear cell-cell junction localization, while surrounding interstitial tissue remains largely negative. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing. Signal highlights epithelial organization and adhesion-associated signaling within renal tubular structures.

Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using Cadherin 1 antibody (clone CDH1/4585). These results demonstrate the foremost specificity of the CDH1/4585 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.

SDS-PAGE analysis of purified, BSA-free Cadherin 1 antibody (clone CDH1/4585) as confirmation of integrity and purity.