- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
E-Cadherin Antibody / CDH1 [clone 1579CT577.150.80] (F53810)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F53810-0.2ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.2 ml | 399 | |
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F53810-0.05ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.05 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, kappa |
| Clone Name | 1579CT577.150.80 |
| Purity | Protein G affinity chromatography |
| UniProt | P12830 |
| Localization | Cytoplasmic, membranous |
| Applications | Western blot : 1:2000-4000 IHC (FFPE) : 1:25 |
| Limitations | This E-Cadherin antibody is available for research use only. |
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Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. E-Cadherin/CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
Titration of the E-Cadherin antibody may be required due to differences in protocols and substrate sensitivity.
A human recombinant protein of amino acids 1-392 was used as the immunogen for the E-Cadherin antibody.
Aliquot the E-Cadherin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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