JUN Antibody / AP-1 Transcription Factor Antibody (RQ7978)

JUN Antibody Laryngeal Squamous Cell Carcinoma IHC. Immunohistochemical staining of FFPE human laryngeal squamous cell carcinoma tissue using JUN Antibody demonstrates predominantly nuclear HRP-DAB brown staining within malignant squamous epithelial cell populations. The staining pattern is consistent with expression of JUN (c-Jun), a key component of the AP-1 transcription factor complex that regulates gene expression involved in cellular proliferation, differentiation, stress responses, and tissue remodeling. Nuclear localization of JUN is consistent with its established role as a DNA-binding transcription factor that mediates signal-dependent transcriptional regulation and cellular adaptation. HIER: boil tissue sections in pH 8 EDTA buffer for 20 minutes and allow to cool before testing.

JUN Antibody Renal Clear Cell Carcinoma IHC. Immunohistochemical staining of FFPE human renal clear cell carcinoma tissue using JUN Antibody demonstrates strong nuclear HRP-DAB brown staining throughout neoplastic cell populations. The staining pattern is consistent with expression of JUN (c-Jun), a DNA-binding component of the AP-1 transcription factor complex that regulates gene expression involved in cellular proliferation, differentiation, stress responses, and signal-dependent transcriptional programs. The prominent nuclear localization observed within tumor cells is characteristic of an active transcription factor and supports the role of JUN in coordinating gene regulatory networks that influence cellular adaptation and tissue remodeling. HIER: boil tissue sections in pH 8 EDTA buffer for 20 minutes and allow to cool before testing.

JUN Antibody Human Pancreatic Cancer IHC. Immunohistochemical staining of FFPE human pancreatic cancer tissue using JUN Antibody demonstrates extensive nuclear HRP-DAB brown staining throughout malignant epithelial cell populations. The staining pattern is consistent with expression of JUN (c-Jun), a DNA-binding component of the AP-1 transcription factor complex that regulates gene expression involved in cellular proliferation, differentiation, stress responses, and signal-dependent transcriptional regulation. The predominantly nuclear localization observed within tumor cells is characteristic of a transcription factor actively engaged in gene regulatory processes and supports the role of JUN in coordinating transcriptional networks associated with cellular adaptation and tumor biology. HIER: boil tissue sections in pH 8 EDTA buffer for 20 minutes and allow to cool before testing.

JUN Antibody Human Spleen IHC. Immunohistochemical staining of FFPE human spleen tissue using JUN Antibody demonstrates widespread nuclear HRP-DAB brown staining throughout splenic cellular populations, with particularly prominent staining surrounding lymphoid follicles. The staining pattern is consistent with expression of JUN (c-Jun), a DNA-binding component of the AP-1 transcription factor complex that regulates gene expression involved in immune responses, cellular activation, differentiation, and stress-responsive signaling pathways. The predominantly nuclear localization is characteristic of a transcription factor and supports the role of JUN in coordinating transcriptional programs within immune-associated tissues. HIER: boil tissue sections in pH 8 EDTA buffer for 20 minutes and allow to cool before testing.

JUN Antibody Human Lung Cancer IHC. Immunohistochemical staining of FFPE human lung cancer tissue using JUN Antibody demonstrates widespread nuclear HRP-DAB brown staining throughout malignant tumor cell populations. The staining pattern is consistent with expression of JUN (c-Jun), a DNA-binding component of the AP-1 transcription factor complex that regulates gene expression involved in cellular proliferation, differentiation, stress responses, and signal-dependent transcriptional programs. The strong nuclear localization observed across neoplastic cells is characteristic of a transcription factor and supports the role of JUN in coordinating gene regulatory networks that influence cellular adaptation, growth, and tumor-associated signaling. HIER: boil tissue sections in pH 8 EDTA buffer for 20 minutes and allow to cool before testing.

JUN Antibody Human Liver Cancer IHC. Immunohistochemical staining of FFPE human liver cancer tissue using JUN Antibody demonstrates widespread nuclear HRP-DAB brown staining throughout malignant hepatocellular populations. The staining pattern is consistent with expression of JUN (c-Jun), a DNA-binding component of the AP-1 transcription factor complex that regulates gene expression involved in cellular proliferation, differentiation, stress responses, and signal-dependent transcriptional regulation. The predominantly nuclear localization observed within tumor cells is characteristic of an active transcription factor and supports the role of JUN in coordinating gene regulatory networks that govern cellular adaptation, growth control, and tissue remodeling. HIER: boil tissue sections in pH 8 EDTA buffer for 20 minutes and allow to cool before testing.

JUN Antibody A431 Cell IF. Immunofluorescent staining of FFPE human A431 cells using JUN Antibody demonstrates strong green nuclear staining throughout the cell population, consistent with localization of JUN (c-Jun), a DNA-binding component of the AP-1 transcription factor complex. JUN functions as a key regulator of gene expression involved in cellular proliferation, differentiation, stress responses, and signal-dependent transcriptional regulation. The highly restricted nuclear staining pattern is characteristic of a transcription factor and supports the role of JUN in controlling transcriptional programs that govern cellular adaptation and signaling responses. DAPI (blue) counterstains cell nuclei. HIER: steam tissue sections in pH 6 citrate buffer for 20 minutes prior to staining.

JUN Antibody U-2 OS and PC-3 Western Blot. Western blot analysis of human U-2 OS (lane 1) and PC-3 (lane 2) cell lysates using JUN Antibody demonstrates distinct bands at approximately 36-43 kDa, consistent with the predicted and commonly observed molecular weight range of JUN (c-Jun). JUN is a DNA-binding component of the AP-1 transcription factor complex that regulates gene expression involved in cellular proliferation, differentiation, stress responses, and signal-dependent transcriptional regulation. Detection of the expected molecular weight band in both cell lines supports expression of JUN and its role as a key regulator of transcriptional programs that govern cellular adaptation and signaling responses.