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Home >> Antibodies >> BRD4 Antibody (N-Terminal Region)

BRD4 Antibody (N-Terminal Region) (F53770)

  Catalog No Formulation Size Price (USD)  
Image F53770-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 369
Image
F53770-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 149
IHC analysis of FFPE human breast carcinoma tissue stained with the BRD4 antibody
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt O60885
Applications IHC (Paraffin) : 1:50-1:100
Limitations This BRD4 antibody is available for research use only.
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Description

BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. The gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people.

Application Notes

Titration of the BRD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 1-30 from the human protein was used as the immunogen for this BRD4 antibody.

Storage

Aliquot the BRD4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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