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  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Home >> Antibodies >> BRAF Antibody

BRAF Antibody (F50795)

  Catalog No Formulation Size Price (USD)  
F50795-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329

F50795-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
Western blot analysis of lysate from MCF-7 cell line using BRAF antibody. Predicted size 85-95 kDa
IHC analysis of FFPE human brain tissue stained with BRAF antibody
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Chicken, Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P15056
Applications Western blot : 1:500
IHC (Paraffin) : 1:10-1:50
Limitations This BRAF antibody is available for research use only.
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Description

BRAF, a member of the RAF subfamily of Ser/Thr protein kinases, is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neurons. This cytoplasmic protein is expressed in brain and testis. Defects in BRAF are involved in a wide range of cancers including lung cancer and non-Hodgkin lymphoma (NHL). This protein contains 1 zinc-dependent phorbol-ester and DAG binding domain.

Application Notes

Titration of the BRAF antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 580-609 from the human protein was used as the immunogen for this BRAF antibody.

Storage

Aliquot the BRAF antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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