- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
BMP2 Antibody / Bone morphogenetic protein 2 [clone AOHD-2] (RQ5386)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ5386 | Antibody in PBS with 0.02% sodium azide and 50% glycerol | 100 ul | 429 |
|
| Availability | 1-2 weeks |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | AOHD-2 |
| Purity | Affinity purified |
| UniProt | P12643 |
| Applications | Western blot : 1:500-1:2000 |
| Limitations | This BMP2 antibody is available for research use only. |
|
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The BMP2 gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [RefSeq]
Optimal dilution of the BMP2 antibody should be determined by the researcher.
A synthetic peptide specific to human BMP2 was used as the immunogen for the BMP2 antibody.
Store the BMP2 antibody at -20oC.
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