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Home >> Antibodies >> Blr1 Antibody / Cxcr5 / Mdr15

Blr1 Antibody / Cxcr5 / Mdr15 (RQ7071)

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  Catalog No Formulation Size Price (USD)  
Image RQ7071 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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IHC staining of FFPE rat lymph node tissue with Blr1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
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IHC staining of FFPE rat lymph node tissue with Blr1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE mouse spleen tissue with Blr1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
Availability 1-3 business days
Species Reactivity Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q04683
Applications Immunohistochemistry (FFPE) : 2-5ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This Blr1 antibody is available for research use only.
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Description

CXCR5 (Chemokine CXC Motif Receptor 5), also known as BLR1 (Burkitt lymphoma receptor 1) and MDR15 (Monocyte derived receptor 15), is a G protein-coupled seven transmembrane receptor for chemokine CXCL13 (also known as BLC) and belongs to the CXC chemokine receptor family. In humans, the CXC-R5 protein is encoded by the CXCR5 gene. The gene plays an essential role in B cell migration. Reif et al.(2002) concluded that their findings defined the mechanism of B-cell relocalization in response to antigen, and established that cell position in vivo can be determined by the balance of responsiveness to chemo-attractants made in separate but adjacent zones. Chan et al.(2003) investigated the expression of chemokines and chemokine receptors in eyes with primary intraocular B-cell lymphoma (PIOL).

Application Notes

Optimal dilution of the Blr1 antibody should be determined by the researcher.

Immunogen

Recombinant mouse protein (amino acids M1-F374) was used as the immunogen for the Blr1 antibody.

Storage

After reconstitution, the Blr1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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