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Home >> Antibodies >> BIN1 Antibody

BIN1 Antibody [clone 99D] (R30005)

  Catalog No Formulation Size Price (USD)  
Image R30005 0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1X PBS 100 ug 359
Western blot testing of BIN1 antibody and Lane 1: rat brain; 2: rat skeletal muscle; 3: rat heart; 4: rat kidney tissue lysate. Predicted molecular weight: ~65kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Ascites
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b
Clone Name 99D
Purity Ascites
Gene ID 274
Applications Western blot : 0.25ug/ml
IHC (Frozen) : 0.5ug/ml-formalin/acetone fixed tissues
Immunocytochemistry : Suitable
Limitations This BIN1 antibody is available for research use only.
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  • Applications : WB, ELISA (peptide)
    Reactivity : Human
    Pred. Reactivity : Cow, Dog, Mouse, Pig, Rat

Description

BIN1(AMPH2) is a novel human gene product with features of a tumor suppressor protein. BIN1 gene to chromosome 2q14. Loss of BIN1 expression appears to be a frequent aberration in human hepatocellular carcinomas . mutations in BIN1 cause centronuclear myopathy by interfering with remodeling of T tubules and/or endocytic membranes, and that the functional interaction between BIN1 and DNM2 is necessary for normal muscle function and positioning of nuclei.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the BIN1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Recombinant polypeptide containing amino acids 189-398 of human BIN1 was used as the immunogen for this BIN1 antibody.

Storage

After reconstitution, the BIN1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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