• Tel: 858.663.9055
  • SeparatorEmail: info@nsjbio.com
  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Order
Home >> Antibodies >> BEX3 Antibody / NGFRAP1 / NADE

BEX3 Antibody / NGFRAP1 / NADE (RQ6827)

NSJ bio Image Pdf Image
  Catalog No Formulation Size Price (USD)  
Image RQ6827 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
Bulk quote request
Flow cytometry testing of human MCF7 cells with BEX3 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= BEX3 antibody.
›
Flow cytometry testing of human MCF7 cells with BEX3 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= BEX3 antibody.
Western blot testing of 1) human HCCT, 2) human HCCP, 3) human MCF7, 4) human HeLa, 5) rat liver, 6) rat L6, 7) mouse liver and 8) mouse C2C12 cell lysate with BEX3 antibody. Predicted molecular weight ~13 kDa (monomer) but commonly observed at ~24 kDa. The dimer may be observed at 40-50 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q00994
Applications Western blot : 1-2ug/ml
Flow cytometry : 1-3ug/million cells
Direct ELISA : 0.1-0.5ug/ml
Limitations This BEX3 antibody is available for research use only.
Review this product on BioCompare and get a $20 Amazon gift card

Description

Protein BEX3 is a protein that in humans is encoded by the BEX3 gene. BEX3 (brain-expressed X-linked protein 3), also called NGFRAP1 (nerve growth factor receptor associated protein 1), NADE (p75NTR-associated death executor) or FAP-1 (Fas-associated phosphatase-1), is a 24 kDa member of the BEX protein family. A nuclear export signal (aa 77-87) allows NGFRAP1 to export bound p75NTR. It is widely expressed, but highest in ovarian granulosa cells, testis, prostate, seminal vesicle and liver. Except for a 13-19 amino acid (aa) rodent Arg/His region at aa 35 that is not found in humans, human NGFRAP1 shares 94% aa identity with mouse and rat NGFRAP1. In humans, a 101 aa isoform with an alternative start site at aa 11 has been described.

Application Notes

Optimal dilution of the BEX3 antibody should be determined by the researcher.

Immunogen

Recombinant human protein (amino acids Q39-H103) was used as the immunogen for the BEX3 antibody.

Storage

After reconstitution, the BEX3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Related Products

   1.   View all BEX3 antibodies

Cross
Bulk Quote Request Form
Name*:
Organization*:
Email*:
Phone Number*:
Catalog No.*:
Comments and Specifics(amount, formulation, etc.)*:
Validation code: Captchapackage Image


Can't read the image? click here to refresh.
    *required field

Your bulk quote request has been submitted successfully!

Please contact us if you have any questions.