Beta Glucuronidase Antibody / Gusb (RQ5581)

Description

Beta Glucuronidase (GUSB) is a lysosomal hydrolase that catalyzes the hydrolysis of beta-D-glucuronic acid residues from glycosaminoglycans, glycoproteins, and other glycoconjugates. This activity plays an essential role in the degradation and recycling of complex carbohydrates within the lysosome, contributing to normal cellular metabolism and turnover of macromolecules.

GUSB is expressed in many tissues and is particularly active in organs with high lysosomal activity, such as liver, kidney, and spleen. Its enzymatic function is critical for maintaining lysosomal homeostasis, and its activity levels are often monitored in studies of carbohydrate metabolism, lysosomal biology, and cellular clearance mechanisms.

The Beta Glucuronidase antibody is a reliable tool for detecting endogenous GUSB in applications such as western blot, immunohistochemistry, and immunofluorescence. Researchers use the Beta Glucuronidase antibody from NSJ Bioreagents to quantify protein expression, evaluate tissue distribution, and investigate lysosomal function under various experimental conditions. With high specificity and consistent performance, the Beta Glucuronidase antibody supports rigorous analysis of carbohydrate processing pathways and lysosomal enzyme regulation.

Application Notes

Optimal dilution of the Beta Glucuronidase antibody should be determined by the researcher.

Immunogen

A human recombinant protein (amino acids Q416-T651) was used as the immunogen for the Beta Glucuronidase antibody.

Storage

After reconstitution, the Beta Glucuronidase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.